Biomarkers of gliomas and their impact on diagnosis, prognosis, and treatment.
Tumors of the central nervous system (CNS) are due to the abnormal growth of cells in the brain or spinal cord that can become malignant and spread by metastases. Gliomas are the most frequent malignant tumors of the CNS, characterized by their heterogeneity and invasiveness. The high lethality of g...
| Published in: | Revista Mexicana de Neurociencia Vol. 22; no. 1; pp. 22 - 30 |
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| Main Authors: | , |
| Format: | Article |
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Academia Mexicana de Neurologia
Jan/Feb2021
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=lth&AN=148765440&site=ehost-live header: @attributes: shortDbName: lth uiTerm: 148765440 longDbName: MedicLatina uiTag: AN controlInfo: bkinfo: jinfo: jid: 16655044 R1Q jtl: Revista Mexicana de Neurociencia issn: 16655044 maglogo: N pubinfo: dt: Jan/Feb2021 vid: 22 iid: 1 pid: 20851 pub: Academia Mexicana de Neurologia artinfo: ui: 148765440 10.24875/RMN.20000029 ppf: 22 ppct: 8 formats: fmt: @attributes: type: P size: 742KB tig: atl: Biomarkers of gliomas and their impact on diagnosis, prognosis, and treatment. aug: au: Álvarez-Guerrero, Argenis F. López-Revilla, Rubén affil: Molecular Biology Division, Instituto Potosino de Investigación Científica y Tecnológica. San Luis Potosí, San Luis Potosí, Mexico su: Biomarkers Gliomas Metastasis Treatment effectiveness Nervous system tumors sug: subj: Biomarkers Gliomas Metastasis Treatment effectiveness Nervous system tumors keyword: Biomarker Diagnosis Glioma Prognosis Treatment Biomarcador Diagnóstico Pronóstico Tratamiento ab: Tumors of the central nervous system (CNS) are due to the abnormal growth of cells in the brain or spinal cord that can become malignant and spread by metastases. Gliomas are the most frequent malignant tumors of the CNS, characterized by their heterogeneity and invasiveness. The high lethality of gliomas is due, among other causes, to the low efficacy of current treatments. The few biomarkers effective for the classification, prognosis, and treatment of the various types of gliomas are a useful tool for their management. New markers are currently being sought to make a more accurate diagnosis and for their potential as therapeutic targets. In this review, we describe the traditional biomarkers and other biomarkers that could be used to improve the diagnosis, prognosis, and treatment of gliomas. Los tumores del sistema nervioso central (SNC) se deben al crecimiento anormal de las células de los tejidos del encéfalo o la médula espinal y pueden malignizarse y diseminarse por metástasis. Los gliomas son los tumores malignos más frecuentes del SNC y se caracterizan por su heterogeneidad e invasividad. La elevada letalidad de los gliomas se debe, entre otras causas, a la baja eficacia de los tratamientos actuales. Los escasos biomarcadores útiles para la clasificación, el pronóstico y el tratamiento de los diversos tipos de gliomas representan una herramienta útil para su manejo. Actualmente se buscan nuevos marcadores para hacer el diagnóstico más preciso y por su potencial como blancos terapéuticos. En esta revisión describimos los biomarcadores tradicionales y algunos otros que podrían mejorar el diagnóstico, pronóstico y tratamiento de los gliomas. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Copyright of Revista Mexicana de Neurociencia is the property of Academia Mexicana de Neurologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Revista Mexicana de Neurociencia holder: Academia Mexicana de Neurologia dt: @attributes: year: 2021 holdings: @attributes: islocal: N |
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