Predicting study duration in clinical trials with a time-to-event endpoint.
In event-driven clinical trials comparing the survival functions of two groups, the number of events required to achieve the desired power is usually calculated using the Freedman formula or the Schoenfeld formula. Then, the sample size and the study duration derived from the required number of even...
| Publicado en: | Statistics in Medicine Vol. 40; no. 10; pp. 2413 - 2422 |
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| Autores principales: | , , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
5/10/2021
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| Acceso en línea: | Ver este registro en EBSCOhost |