Normal fat mass cannot be reliably estimated in typical pharmacokinetic studies.

Purpose: An influential covariate for pharmacokinetics is (body) size. Recently, the method of estimation of normal fat mass (NFM) has been advocated. Here, the relative contribution of fat mass, estimated as a fraction fat (Ffat), is used to explain differences in pharmacokinetic parameters. This c...

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Bibliographic Details

Published in:	European Journal of Clinical Pharmacology Vol. 77; no. 5; pp. 727 - 734
Main Authors:	Wasmann, Roeland E., Svensson, Elin M., Schalkwijk, Stein J., Brüggemann, Roger J., ter Heine, Rob
Format:	equations & formulas research tables/charts Journal Article
Published:	Springer Nature May2021
Online Access:	View this record in EBSCOhost