Normal fat mass cannot be reliably estimated in typical pharmacokinetic studies.
Purpose: An influential covariate for pharmacokinetics is (body) size. Recently, the method of estimation of normal fat mass (NFM) has been advocated. Here, the relative contribution of fat mass, estimated as a fraction fat (Ffat), is used to explain differences in pharmacokinetic parameters. This c...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 77; no. 5; pp. 727 - 734 |
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| Autores principales: | , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Springer Nature
May2021
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| Acceso en línea: | Ver este registro en EBSCOhost |