Relative oxygen extraction fraction (rOEF) MR imaging reveals higher hypoxia in human epidermal growth factor receptor (EGFR) amplified compared with non-amplified gliomas.

Purpose: Epidermal growth factor receptor (EGFR) amplification promotes gliomagenesis and is linked to lack of oxygen within the tumor microenvironment. Using hypoxia-sensitive spin-and-gradient echo echo-planar imaging and perfusion MRI, we investigated the influence of EGFR amplification on tissue...

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Publicado en:	Neuroradiology Vol. 63; no. 6; pp. 857 - 869
Autores principales:	Oughourlian, Talia C., Yao, Jingwen, Hagiwara, Akifumi, Nathanson, David A., Raymond, Catalina, Pope, Whitney B., Salamon, Noriko, Lai, Albert, Ji, Matthew, Nghiemphu, Phioanh L., Liau, Linda M., Cloughesy, Timothy F., Ellingson, Benjamin M.
Formato:	diagnostic images pictorial research tables/charts Journal Article
Publicado:	Springer Nature Jun2021
Acceso en línea:	Ver este registro en EBSCOhost