Novel therapeutic approaches for the primary hyperoxalurias.

Loss-of-function mutations in three genes, involved in the metabolic pathway of glyoxylate, result in increased oxalate production and its crystallization in the form of calcium oxalate. This leads to three forms of primary hyperoxaluria—an early-onset inherited kidney disease with wide phenotypic v...

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Publicado en:Pediatric Nephrology Vol. 36; no. 9; pp. 2593 - 2607
Autores principales: Belostotsky, Ruth, Frishberg, Yaacov
Formato: pictorial review tables/charts Journal Article
Publicado: Springer Nature Sep2021
Acceso en línea:Ver este registro en EBSCOhost