New dihydrobenzofuranoid from the marine-derived fungus Aspergillus ustus KMM 4664.
One new dihydrobenzofuran derivative (1), known depsipeptide emericellamide A (2), three known drimanes (3–5) and two artifact drimane derivatives (6, 7) were isolated from the marine-derived fungus Aspergillus ustus KMM 4664. Their structures were determined by detailed analysis of spectroscopic da...
| Publicado en: | Natural Product Research Vol. 35; no. 19; pp. 3332 - 3336 |
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| Autores principales: | , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Taylor & Francis Ltd
Oct2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=152760058&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 152760058 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14786419 RFT jtl: Natural Product Research issn: 14786419 maglogo: Y pubinfo: dt: Oct2021 vid: 35 iid: 19 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 152760058 10.1080/14786419.2019.1689496 152760058 ppf: 3332 ppct: 4 formats: tig: atl: New dihydrobenzofuranoid from the marine-derived fungus Aspergillus ustus KMM 4664. aug: au: Oleinikova, Galina K. Zhuravleva, Olesya I. Berdyshev, Dmitrii V. Menzorova, Natalia I. Popov, Roman S. Denisenko, Vladimir A. Kirichuk, Natalya N. Afiyatullov, Shamil Sh. affil: Laboratory of Chemistry of Microbial Metabolites, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Vladivostok, Russian Federation sug: ab: One new dihydrobenzofuran derivative (1), known depsipeptide emericellamide A (2), three known drimanes (3–5) and two artifact drimane derivatives (6, 7) were isolated from the marine-derived fungus Aspergillus ustus KMM 4664. Their structures were determined by detailed analysis of spectroscopic data and by comparison with related known compounds. The absolute configuration of 1 was determined by time-dependent density functional theory (TD-DFT) calculations of ECD spectra. Compound 7 showed significant ability of the inhibition of spermatozoa to fertilize egg-cells of the sea urchin Strongylocentrotus intermedius with IC50 value 21 µM. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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