Glycemic response, satiety, gastric secretions and emptying after bread consumption with water, tea or lemon juice: a randomized crossover intervention using MRI.

Purpose: Numerous studies, including our previous work with lemon juice, have reported that low-pH meals reduce the glycemic response to starchy foods. However, the underlying mechanism is not yet understood. Tea, for its polyphenol content, has also been investigated. The main objective of this res...

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Publicado en:European Journal of Nutrition Vol. 61; no. 3; pp. 1621 - 1637
Autores principales: Freitas, Daniela, Boué, François, Benallaoua, Mourad, Airinei, Gheorghe, Benamouzig, Robert, Lutton, Evelyne, Jourdain, Laurène, Dubuisson, Rose-Marie, Maître, Xavier, Darrasse, Luc, Le Feunteun, Steven
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Apr2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2022
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      pub: Springer Nature
      place: New York, New York
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        atl: Glycemic response, satiety, gastric secretions and emptying after bread consumption with water, tea or lemon juice: a randomized crossover intervention using MRI.
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          Freitas, Daniela
          Boué, François
          Benallaoua, Mourad
          Airinei, Gheorghe
          Benamouzig, Robert
          Lutton, Evelyne
          Jourdain, Laurène
          Dubuisson, Rose-Marie
          Maître, Xavier
          Darrasse, Luc
          Le Feunteun, Steven
        affil: Université Paris-Saclay, INRAE, AgroParisTech, UMR SayFood, 78850, Thiverval-Grignon, France
      sug:
        subj:
          Gastrointestinal Motility
          Appetite
          Glycemic Index
          Bread
          Water
          Tea
          Lemon
          Fruit Juices
          Human
          Randomized Controlled Trials
          Random Assignment
          Crossover Design
          Blood Glucose
          Magnetic Resonance Imaging
          Visual Analog Scaling
          Gastric Juice
          Glucans
          Acid-Base Equilibrium
          Amylases
      ab: Purpose: Numerous studies, including our previous work with lemon juice, have reported that low-pH meals reduce the glycemic response to starchy foods. However, the underlying mechanism is not yet understood. Tea, for its polyphenol content, has also been investigated. The main objective of this research was to concurrently study gastric emptying, appetite perceptions and glycemic responses to bread consumed with water, tea, or lemon juice. Methods: In this randomized, crossover intervention, ten participants consumed equal portions of bread (100 g) with 250 mL of water, water-diluted lemon juice, or black tea at breakfast. Gastric volumes, blood glucose concentrations and appetite perceptions were alternately assessed over 180 min using magnetic resonance imaging, the finger-prick method and visual analogue scales, respectively. Results: Compared to water, lemon juice led to a 1.5 fold increase of the volume of gastric contents, 30 min after the meal (454.0 ± 18.6 vs. 298.4 ± 19.5 mL, x ¯ ± SEM P < 0.00001). Gastric emptying was also 1.5 times faster (P < 0.01). Conversely, lemon juice elicited a lower glycemic response than water (blood glucose concentrations at t = 55 min were 35% lower, P = 0.039). Tea had no effect. Changes in appetite perceptions and gastric volumes correlated well, but with no significant differences between the meals. Conclusions: Lemon juice lowered the glycemic response and increased both gastric secretions and emptying rate. The results are compatible with the hypothesis that the reduction of the glycemic response is mainly due to the interruption of starch hydrolysis via the acid-inhibition of salivary α-amylase. Trial registration number: NCT03265392, August 29, 2017.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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