Effects of Pharmacologic Treatment for Neonatal Abstinence Syndrome on DNA Methylation and Neurobehavior: A Prospective Cohort Study.

Objective: To determine whether pharmacologic treatment for neonatal abstinence syndrome (NAS) is associated with changes in DNA methylation (DNAm) of the mu-opioid receptor gene (OPRM1) and improvements in neonatal neurobehavior.Study Design: Buccal swabs were collected from 37 neonates before and...

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Bibliographic Details

Published in:	Journal of Pediatrics Vol. 243; pp. 21 - 27
Main Authors:	Camerota, Marie, Davis, Jonathan M., Dansereau, Lynne M., Oliveira, Erica L., Padbury, James F., Lester, Barry M.
Format:	research Journal Article
Published:	Elsevier B.V. Apr2022
Online Access:	View this record in EBSCOhost