Effects of Pharmacologic Treatment for Neonatal Abstinence Syndrome on DNA Methylation and Neurobehavior: A Prospective Cohort Study.

Objective: To determine whether pharmacologic treatment for neonatal abstinence syndrome (NAS) is associated with changes in DNA methylation (DNAm) of the mu-opioid receptor gene (OPRM1) and improvements in neonatal neurobehavior.Study Design: Buccal swabs were collected from 37 neonates before and...

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Publicado en:Journal of Pediatrics Vol. 243; pp. 21 - 27
Autores principales: Camerota, Marie, Davis, Jonathan M., Dansereau, Lynne M., Oliveira, Erica L., Padbury, James F., Lester, Barry M.
Formato: research Journal Article
Publicado: Elsevier B.V. Apr2022
Acceso en línea:Ver este registro en EBSCOhost