What Pupils Remember: Exploring the Relationship between Dynamic Pupil Parameters and Self-Reported History of Mild Traumatic Brain Injury.
Background: Whether a history of mild traumatic brain injury (mTBI) affects pupil dynamics that could confound the interpretation of pupil data in other causes of visual dysfunction is unknown. We investigated the relationship between history of mTBI and pupil dynamics recorded with highdefinition p...
| Publicado en: | Optometry & Visual Performance Vol. 10; no. 2; pp. 98 - 108 |
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| Autores principales: | , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Optometric Extension Program
Jun2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=158174880&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 158174880 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23253479 HOOW jtl: Optometry & Visual Performance issn: 23253479 maglogo: N pubinfo: dt: Jun2022 vid: 10 iid: 2 pid: 46881 pub: Optometric Extension Program place: Lutherville Timonium, Maryland artinfo: ui: 158174880 158174880 158174880 158174880 ppf: 98 ppct: 10 formats: tig: atl: What Pupils Remember: Exploring the Relationship between Dynamic Pupil Parameters and Self-Reported History of Mild Traumatic Brain Injury. aug: au: Cisarik, Patricia M. Yi Pang affil: Southern College of Optometry Memphis, Tennessee sug: subj: Pupil Physiology Self Report Brain Injuries Human Adult Middle Age Aged Aged, 80 and Over Multiple Regression Radiography Methods Pupil Radiography Multiple Linear Regression Data Analysis Software Nonparametric Statistics Confidence Intervals Descriptive Statistics Male Female Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Background: Whether a history of mild traumatic brain injury (mTBI) affects pupil dynamics that could confound the interpretation of pupil data in other causes of visual dysfunction is unknown. We investigated the relationship between history of mTBI and pupil dynamics recorded with highdefinition pupillography. Methods:Subjects (n = 137) aged 19 to 81 years were enrolled from attendees of an optometric meeting in 2016. The data collected included: ocular and systemic health histories, current medications, history of TBI, and pupil dynamics using the automated afferent pupillary defect protocol of the RAPDx (Konan Medical). Multiple regressions with backward analysis were used to identify factors that predicted pupil dynamics. Results: Thirty-five subjects reported positive history of mTBI (15 reported more than 1 mTBI). None of the pupil parameters assessed for either eye were predicted by history of mTBI. Time from most recent head injury to pupil testing predicted only latency of constriction onset of each eye (right eye: P = 0.02, R2 = 0.214; left eye: P = 0.02, R2 = 0.187). Age and time from most recent head injury to pupil testing predicted latency of constriction onset for each eye in those reporting head injury (right eye: adjusted R2 = 0.23, P = 0.02; left eye: adjusted R2 = 0.26, P = 0.01). Conclusions: Dynamic pupil parameters elicited with a bright white stimulus were not predicted by history of mTBI. Time from most recent mTBI to date of pupil testing may partially predict latency of pupil constriction, and longer times from most recent mTBI to date of pupil testing may be associated with slower redilation velocities. However, the influence of age on the association between time from most recent mTBI and velocity of redilation in this study sample is unknown. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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