Conjugation to a cell-penetrating peptide drives the tumour accumulation of the GLP1R antagonist exendin(9-39).
Purpose: Exendin, an analogue of the glucagon-like peptide 1 (GLP1), is an excellent tracer for molecular imaging of pancreatic beta cells and beta cell-derived tumours. The commonly used form, exendin-4, activates the GLP1 receptor and causes internalisation of the peptide-receptor complex. As a co...
| Publicado en: | European Journal of Nuclear Medicine & Molecular Imaging Vol. 50; no. 4; pp. 996 - 1005 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Mar2023
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| Acceso en línea: | Ver este registro en EBSCOhost |