The Antitumor Effect of Topotecan Loaded Thiolated Chitosan-Dextran Nanoparticles for Intravitreal Chemotherapy: A Xenograft Retinoblastoma Model.

Purpose: This research intended to fabricate the thiolated chitosan-dextran nanoparticles (NPs) containing topotecan (TPH-CMD-TCS-NPs) to assess the ability of NPs in improving the efficacy of intravitreal chemotherapy of retinoblastoma in a rabbit xenograft model. Methods: The coacervation process...

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Bibliographic Details
Published in:Journal of Ophthalmic & Vision Research Vol. 18; no. 1; pp. 68 - 81
Main Authors: Delrish, Elham, Jabbarvand, Mahmoud, Ghassemi, Fariba, Amoli, Fahimeh Asadi, Atyabi, Fatemeh, Keshel, Saeed Heidari, Lashay, Alireza, Mirzazadeh Tekie, Farnaz Sadat, Soleimani, Masoud, Dinarvand, Rassoul
Format: diagnostic images pictorial research tables/charts Journal Article
Published: Knowledge E DMCC Jan-Mar2023
Online Access:View this record in EBSCOhost