Purification of Protein by HIC: Mechanistic Modeling for Improved Understanding and Process Optimization.

Hydrophobic interaction chromatography (HIC) is a separation technique widely used for the purification of therapeutic proteins. The main leverages identified to operate HIC processes are solution pH and ionic strength. In this article, the authors show that simplistic mathematical models derived fr...

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Bibliographic Details

Published in:	BioPharm International Vol. 36; no. 4; pp. 22 - 30
Main Authors:	NICOUD, LUCRÈCE, LE GUENNEC, YOHANN, NICOUD, EDOUARD, CARDILLO, ANTONIO, LIETTA, ELENA, INNOCENTI, ELISA, PIERI, ALESSANDRO
Format:	equations & formulas pictorial research tables/charts Journal Article
Published:	MJH Life Sciences Apr2023
Online Access:	View this record in EBSCOhost