| Sumario: | Introduction: Staff nurses play an important role in prevention of infection of patients by paying careful attention to hand hygiene, ensuring careful administration of prescribed antibiotics and by following procedures to reduce the risks associated with patient care devices. Aim: To evaluate compliance of nurses regarding standard precautions of infection control. Method: Descriptive cross-sectional hospital-based study was conducted at ELdaein teaching hospital. The sample consisted of 60 nurses. Data was collected though observational checklist. Result: nurses' compliance with standard precautions of infection control was good Mean ± SD (2.92, 0.512). Conclusion: The nurses had a good level of compliance with standard precautions of infection control while most of nurseswere not compliance with washinghands before wears gloves, wear masks and protective eye patch or goggle when performing operations/procedures that might induce spraying of blood, body fluid, secretions, and excretions due to lack of personal protective equipment. The findings suggest the important of continuous teaching, training, and workshop courses to improve nurses' compliance with standard precautions of infection control and to supply all personal protective equipment which helps the nurses to comply with standard preparations of infection control.
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