Chemical Confirmation of a Pentavalent Phosphorane in Complex with β-Phosphoglucomutase.
The article focuses on a study related to chemical confirmation of a pentavalent phosphorane in complex with β-phosphoglucomutase. The catalytic power of enzymes originates from their ability to stabilize high-energy transition states and intermediates. Results validate original assignment of the β-...
| Publicado en: | Journal of the American Chemical Society Vol. 127; no. 15; pp. 5298 - 5300 |
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| Autores principales: | , , , , |
| Formato: | Artículo |
| Publicado: |
American Chemical Society
4/20/2005
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=16827508&site=ehost-live header: @attributes: shortDbName: hlh uiTerm: 16827508 longDbName: Humanities International Complete uiTag: AN controlInfo: bkinfo: jinfo: jid: 00027863 ACS jtl: Journal of the American Chemical Society issn: 00027863 maglogo: N pubinfo: dt: 4/20/2005 vid: 127 iid: 15 pid: 997 pub: American Chemical Society artinfo: ui: 16827508 10.1021/ja0509073 ppf: 5298 ppct: 2 formats: tig: atl: Chemical Confirmation of a Pentavalent Phosphorane in Complex with β-Phosphoglucomutase. aug: au: Tremblay, Lee W. Zhang, Guofeng Dai, Jianying Dunaway-Mariano, Debra Allen, Karen N. affil: Boston University School of Medicine. University of New Mexico. su: Glucose Phosphorus Enzymes Optical diffraction Proteins Catalysts sug: subj: Glucose Phosphorus Enzymes Optical diffraction Proteins Catalysts ab: The article focuses on a study related to chemical confirmation of a pentavalent phosphorane in complex with β-phosphoglucomutase. The catalytic power of enzymes originates from their ability to stabilize high-energy transition states and intermediates. Results validate original assignment of the β-PGM-βD-glucose-6-phosphate-1-phosphorane complex to the previously reported X-ray diffraction data. Dataset and protein model phases only shows electron density of identical magnitude for both atoms assigned as phosphorus. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y dt: @attributes: year: 2005 holdings: @attributes: islocal: N |
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