| Sumario: | Background: Chronic diseases with high prevalence and mortality rates negatively affect individuals' quality of life and perceptions of self-efficacy. Aim: The study aimed to evaluate the perceptions of self-efficacy and quality of life in individuals with chronic diseases and determine their needs. Method: This study was descriptive research. The research was conducted in the internal medicine, neurology, chest diseases, and cardiology clinics of two state hospitals. The research sample consisted of 130 patients.Data tools were the Patient Information Survey, the Strategies Used by Patients to Promote Health scale, and the SF-36 Quality of Life Scale. Results: The patients were male (53.8%), and 45.4% were older than 70. The Stress Reduction subscale of the selfefficacy scale score was 29.95 ± 11.99, the Making Decision subscale score was 8.90 ± 3.62, and the Positive Attitude subscale score was 49.73 ± 18.92. The self-efficacy scale score was 88.58 ± 33.80. Perception of selfefficacy was moderate in individuals with chronic disease. Physical Role, General Health, and Bodily Pain subdimensions were the most negatively affected. Physical Functioning, Social Functioning, and Energy dimensions were moderately affected. Analysis revealed a positive correlation between self-efficacy scale total scores and SF-36 Quality of Life Scale scores (r = 0.45-0.99, p = 0.000). Conclusions: Individuals with chronic diseases need support in managing physical problems, activities of daily living, and coping with symptoms. In addition, to improve the quality of life, it is recommended to determine stressors and provide counseling on stress management.
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