Structural modifications toward improved lead-203/lead-212 peptide-based image-guided alpha-particle radiopharmaceutical therapies for neuroendocrine tumors.

Purpose: The lead-203 (203Pb)/lead-212 (212Pb) elementally identical radionuclide pair has gained significant interest in the field of image-guided targeted alpha-particle therapy for cancer. Emerging evidence suggests that 212Pb-labeled peptide-based radiopharmaceuticals targeting somatostatin rece...

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Bibliographic Details
Published in:European Journal of Nuclear Medicine & Molecular Imaging Vol. 51; no. 4; pp. 1147 - 1163
Main Authors: Lee, Dongyoul, Li, Mengshi, Liu, Dijie, Baumhover, Nicholas J., Sagastume, Edwin A., Marks, Brenna M., Rastogi, Prerna, Pigge, F. Christopher, Menda, Yusuf, Johnson, Frances L., Schultz, Michael K.
Format: Journal Article
Published: Springer Nature Mar2024
Online Access:View this record in EBSCOhost