Topical phenytoin for wound healing: a narrative review.
Background In 1937, oral phenytoin medication was introduced as an anti-epileptic drug. For many years, researchers have shown interest in how topical phenytoin may be used to promote wound healing in various wounds. Purpose This review article aims to summarise and critically appraise the clinical...
| Publicado en: | Wound Practice & Research Vol. 32; no. 2; pp. 66 - 79 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | pictorial research systematic review tables/charts Journal Article |
| Publicado: |
Cambridge Publishing
Jun2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=177917976&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 177917976 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18376304 639G jtl: Wound Practice & Research issn: 18376304 maglogo: N pubinfo: dt: Jun2024 vid: 32 iid: 2 pid: 66266 pub: Cambridge Publishing artinfo: ui: 177917976 177917976 177917976 10.33235/wpr.32.2.66-78 177917976 ppf: 66 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Topical phenytoin for wound healing: a narrative review. aug: au: Qadirifard, Mohammad S. Qadirifard, Mohammad Tavakoli, Ghazal Mojeni, Fariba A. Mohagheghi, Seyede Z. Rafiei, Seyyed K. S. Salimi, Yasaman Taherinik, Reza Sheikhzadeh, Farzad Pakrou, Neda Poudineh, Mohadeseh Gholami, Kosar Dianati, Maryam Mehrabi, Hoda Fathi, Mobina Deravi, Niloofar affil: Department of Nursing and Midwifery, Islamic Azad University, Tehran, Iran sug: subj: Administration, Topical Phenytoin Therapeutic Use Wound Healing Drug Effects Wound Care Phenytoin Pharmacodynamics Molecular Structure Anticonvulsants Health Promotion Wounds and Injuries Human Drug Efficacy Tretinoin Silver Sulfadiazine Honey Dexamethasone Povidone-Iodine Diabetic Foot Platelet-Derived Growth Factor Epidermal Growth Factors Collagen Systematic Review PubMed ab: Background In 1937, oral phenytoin medication was introduced as an anti-epileptic drug. For many years, researchers have shown interest in how topical phenytoin may be used to promote wound healing in various wounds. Purpose This review article aims to summarise and critically appraise the clinical evidence available on the effects of topical phenytoin on wound healing. Methods By using the keywords phenytoin, injuries, wound, wound care, and wound healing, we extracted articles published up to April 2022 through a search in PubMed, ISI Web of Science, SID, Google Scholar and Scopus. Result We identified 17 studies performed on human subjects and eight on rats. Phenytoin effectiveness is also compared with other wound care substances, including tretinoin, silver sulfadiazine, EUSOL, honey, dexamethasone and hypericin. Conclusion This review illustrated the significant effects and rare adverse events of topical phenytoin on wound healing. pubtype: Academic Journal doctype: pictorial research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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