Melatonin does not reduce delirium severity in hospitalized older adults: Results of a randomized placebo‐controlled trial.

Background: Delirium is common in older inpatients, causing distress, cognitive decline, and death. Current therapies are unsatisfactory, limited by lack of efficacy and adverse effects. There is an urgent need for effective delirium treatment. Sleep wake cycle is disturbed in delirium; endogenous M...

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