How to Balance Prognostic Factors in Controlled Phase II Trials: Stratified Permuted Block Randomization or Minimization? An Analysis of Clinical Trials in Digestive Oncology.

In controlled phase II trials, major prognostic factors need to be well balanced between arms. The main procedures used are SPBR (Stratified Permuted Block Randomization) and minimization. First, we provide a systematic review of the treatment allocation procedure used in gastrointestinal oncology c...

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Publicado en:	Current Oncology Vol. 31; no. 6; pp. 3513 - 3529
Autores principales:	Martin, Elodie, Le Malicot, Karine, Guérin-Charbonnel, Catherine, Bocquet, François, Bouché, Olivier, Turpin, Anthony, Aparicio, Thomas, Legoux, Jean-Louis, Dahan, Laetitia, Taieb, Julien, Lepage, Côme, Dourthe, Louis-Marie, Pétorin, Caroline, Bourgeois, Vincent, Raoul, Jean-Luc, Seegers, Valérie
Formato:	Journal Article
Publicado:	MDPI Jun2024
Acceso en línea:	Ver este registro en EBSCOhost