Donepezil promotes skin flap survival through activation of the HIF‐1α/VEGF signalling pathway.

Flaps are mainly used to repair wounds in the clinical setting but can sometimes experience ischaemic necrosis postoperatively. This study investigated whether donepezil, an acetylcholinesterase inhibitor, can enhance the survival rate of flaps. We randomly allocated 36 rats into control, low‐dose (...

Full description

Bibliographic Details
Published in:Wound Repair & Regeneration Vol. 32; no. 4; pp. 500 - 511
Main Authors: Lin, Hang, Wang, Kaitao, Yang, Jialong, Wang, An, Deng, Jiapeng, Lin, Dingsheng
Format: pictorial research tables/charts Journal Article
Published: Wiley-Blackwell Jul2024
Online Access:View this record in EBSCOhost