Relationship between the Mediterranean Diet and Vascular Function in Subjects with and without Increased Insulin Resistance.

(1) The main aim of this study was to analyze the relationship of the Mediterranean diet (MD) with vascular function in participants with and without increased insulin resistance (IR) in the Spanish population. A secondary aim was to study differences by gender. (2) Methods: Data were analyzed from...

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Publicado en:Nutrients Vol. 16; no. 18; pp. 3106 - 3124
Autores principales: Gómez-Sánchez, Marta, Gómez-Sánchez, Leticia, Llamas-Ramos, Rocío, Rodríguez-Sánchez, Emiliano, García-Ortiz, Luis, Martí-Lluch, Ruth, Rodríguez, María Cortés, Llamas-Ramos, Inés, Gómez-Marcos, Manuel A.
Formato: research tables/charts Journal Article
Publicado: MDPI Sep2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2024
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        atl: Relationship between the Mediterranean Diet and Vascular Function in Subjects with and without Increased Insulin Resistance.
      aug:
        au:
          Gómez-Sánchez, Marta
          Gómez-Sánchez, Leticia
          Llamas-Ramos, Rocío
          Rodríguez-Sánchez, Emiliano
          García-Ortiz, Luis
          Martí-Lluch, Ruth
          Rodríguez, María Cortés
          Llamas-Ramos, Inés
          Gómez-Marcos, Manuel A.
        affil: Home Hospitalization Service, Marqués of Valdecilla University Hospital, s/n, 39008 Santander, Spain
      sug:
        subj:
          Mediterranean Diet
          Insulin Resistance
          Spanish Persons
          Sex Factors
          Blood Vessels Physiology
          Cardiovascular System Physiology
          Human
          Male
          Female
          Funding Source
          Triglycerides Blood
          Questionnaires
          Arterial Stiffness
          Pulse Wave Velocity
          Cardiovascular Risk Factors
          T-Tests
          Chi Square Test
          Multiple Linear Regression
          Data Analysis Software
          Descriptive Statistics
          Male
          Female
      ab: (1) The main aim of this study was to analyze the relationship of the Mediterranean diet (MD) with vascular function in participants with and without increased insulin resistance (IR) in the Spanish population. A secondary aim was to study differences by gender. (2) Methods: Data were analyzed from 3401 subjects in the EVA, MARK, and EVIDENT studies (mean age = 60 years and 57% men). IR was evaluated with the triglyceride and glucose index (TyG index). TyG index = Ln [(fasting triglyceride mg/dL × fasting glucose mg/dL)/2]. The MD was measured against the MEDAS questionnaire, with the 14 items used in the PREDIMED study. Vascular stiffness was estimated with the brachial–ankle pulse wave velocity (baPWV) and the cardio ankle vascular index (CAVI) using the Vasera VS-1500®. (3) Results: The mean MEDAS value was 5.82 ± 2.03; (men: 5.66 ± 2.06; women: 6.04 ± 1.99; p < 0.001). MD adherence was 36.8% (men: 34.2%; women: 40.3%; p < 0.001). The mean baPWV value was 14.39 ± 2.78; (men: 14.50 ± 2.65; women: 14.25 ± 2.93; p = 0.005). A baPWV value ≥ 14.5 m/s was found in 43.4% (men: 43.6%; women: 40.0%; p = 0.727). The mean CAVI value was 8.59 ± 1.28; (men: 8.75 ± 1.28; women: 8.37 ± 1.26; p < 0.001). CAVI values ≥ 9 were present in 39.0% (men: 44.4%; women: 31.7%; p < 0.001). The mean value of the TGC/G index was 10.93 ± 1.39; (men: 11.08 ± 1.33; women: 10.73 ± 1.43; p < 0.001). IR was found in 49.9%. The average value of the MD score value was negatively associated with baPWV and CAVI in all groups analyzed (<0.05), except in the group of women with insulin resistance. (4) Conclusions: The results suggest that MD adherence is negatively associated with the vascular stiffness parameters analyzed in all the groups studied except the group of women with insulin resistance.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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