Asymptotically exact fit for linear mixed model in genetic association studies.

The linear mixed model (LMM) has become a standard in genetic association studies to account for population stratification and relatedness in the samples to reduce false positives. Much recent progresses in LMM focused on approximate computations. Exact methods remained computationally demanding and...

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Detalles Bibliográficos
Publicado en:Genetics Vol. 228; no. 2; pp. 1 - 13
Autores principales: Guan, Yongtao, Levy, Daniel
Formato: computer program equations & formulas research tables/charts Journal Article
Publicado: Oxford University Press / USA Oct2024
Acceso en línea:Ver este registro en EBSCOhost