Asymptotically exact fit for linear mixed model in genetic association studies.

The linear mixed model (LMM) has become a standard in genetic association studies to account for population stratification and relatedness in the samples to reduce false positives. Much recent progresses in LMM focused on approximate computations. Exact methods remained computationally demanding and...

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Bibliographic Details
Published in:Genetics Vol. 228; no. 2; pp. 1 - 13
Main Authors: Guan, Yongtao, Levy, Daniel
Format: computer program equations & formulas research tables/charts Journal Article
Published: Oxford University Press / USA Oct2024
Online Access:View this record in EBSCOhost