| Sumario: | Dyshidrotic eczema, also known as pompholyx or eczema of the palms and soles, is a vesicular and irritating palmoplantar dermatitis that can be recurring or chronic. Although the cause is unknown, it appears to be related to seasonal fluctuations and atopy. Other skin disorders associated with dyshidrotic eczema include atopic dermatitis, contact dermatitis, and bacterial and fungal infections. Clinically, these patients experience pruritus before developing visible lesions. When the lesions first appear, they have vesicles or bullae that are densely packed and symmetrical. Other common locations for them are the soles of the feet, the lateral aspects of the toes, and the palms and lateral aspects of the fingers. Histologically, the epidermis. Homeopathy is a holistic system of medicine that works on the principle of 'like cures like'. The present case report depicts a case of a 17-year-old College patient suffering from skin eruption with a clear fluid-filled blister on both the hand and sole especially the dorsum of the hand and sole. Based on the totality of symptoms, individualized homeopathic medicine Rhus tox 30C was prescribed and the patient recovered. Abbreviation: allergic dermatitis, contact dermatitis
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