The underlying neuropsychological and neural correlates of the impaired Chinese reading skills in children with attention deficit hyperactivity disorder.

Impaired basic academic skills (e.g., word recognition) are common in children with Attention Deficit Hyperactivity Disorder (ADHD). The underlying neuropsychological and neural correlates of impaired Chinese reading skills in children with ADHD have not been substantially explored. Three hundred an...

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Publicado en:European Child & Adolescent Psychiatry Vol. 33; no. 11; pp. 3979 - 3993
Autores principales: Wu, Zhao-Min, Wang, Peng, Zhong, Yun-Yu, Liu, Yun, Liu, Xue-Chun, Wang, Jiu-Ju, Cao, Xiao-Lan, Liu, Lu, Sun, Li, Yang, Li, Zang, Yu-Feng, Qian, Ying, Cao, Qing-Jiu, Wang, Yu-Feng, Yang, Bin-Rang
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Nov2024
Acceso en línea:Ver este registro en EBSCOhost
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        atl: The underlying neuropsychological and neural correlates of the impaired Chinese reading skills in children with attention deficit hyperactivity disorder.
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        au:
          Wu, Zhao-Min
          Wang, Peng
          Zhong, Yun-Yu
          Liu, Yun
          Liu, Xue-Chun
          Wang, Jiu-Ju
          Cao, Xiao-Lan
          Liu, Lu
          Sun, Li
          Yang, Li
          Zang, Yu-Feng
          Qian, Ying
          Cao, Qing-Jiu
          Wang, Yu-Feng
          Yang, Bin-Rang
        affil: https://ror.org/0409k5a27 Shenzhen Childrens Hospital, Shenzhen, China
      sug:
        subj:
          Neuropsychological Tests
          Attention Deficit Hyperactivity Disorder Physiopathology
          Reading China
          Brain Physiopathology
          Human
          Male
          Female
          Child
          Funding Source
          China
          Mediation Analysis
          Cognition Disorders
          Default Mode Network
          Comparative Studies
          Magnetic Resonance Imaging
          Child: 6-12 years
          Male
          Female
      ab: Impaired basic academic skills (e.g., word recognition) are common in children with Attention Deficit Hyperactivity Disorder (ADHD). The underlying neuropsychological and neural correlates of impaired Chinese reading skills in children with ADHD have not been substantially explored. Three hundred and two children with ADHD (all medication-naïve) and 105 healthy controls underwent the Chinese language skill assessment, and 175 also underwent fMRI scans (84 ADHD and 91 controls). Between-group and mediation analyses were applied to explore the interrelationships of the diagnosis of ADHD, cognitive dysfunction, and impaired reading skills. Five ADHD-related brain functional networks, including the default mode network (DMN) and the dorsal attention network (DAN), were built using predefined regions of interest. Voxel-based group-wise comparisons were performed. The ADHD group performed worse than the control group in word-level reading ability tests, with lower scores in Chinese character recognition (CR) and word chains (WS) (all P < 0.05). With full-scale IQ and sustained attention in the mediation model, the direct effect of ADHD status on the CR score became insignificant (P = 0.066). The underlying neural correlates for the orthographic knowledge (OT) and CR differed between the ADHD and the control group. The ADHD group tended to recruit more DMN regions to maintain their reading performance, while the control group seemed to utilize more DAN regions. Children with ADHD generally presented impaired word-level reading skills, which might be caused by impaired sustained attention and lower IQ. According to the brain functional results, we infer that ADHD children might utilize a different strategy to maintain their orthographic knowledge and character recognition performance.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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