Bullous Pyoderma Gangrenosum Associated with Antiphospholipid Syndrome: A Case Report and Literature Review.

We report a rare case of a middle-aged Omani woman who was known to have primary antiphospholipid syndrome, glucose-6-phosphate dehydrogenase deficiency, and iron deficiency anaemia. Cannulation attempts caused bulla which progressed to ulceration. A pathergy phenomenon with high suspicion of pyoder...

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Publicado en:Oman Medical Journal Vol. 39; no. 4; pp. 14 - 20
Autores principales: Al-Bahrani, Mayar, Alwashahi, Yousuf, Almoqbali, Ahmed, Alajmi, Asma
Formato: case study pictorial Journal Article
Publicado: Oman Medical Specialty Board Jul2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2024
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      pub: Oman Medical Specialty Board
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        10.5001/omj.2024.26
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        atl: Bullous Pyoderma Gangrenosum Associated with Antiphospholipid Syndrome: A Case Report and Literature Review.
      aug:
        au:
          Al-Bahrani, Mayar
          Alwashahi, Yousuf
          Almoqbali, Ahmed
          Alajmi, Asma
        affil: Family Medicine General Foundation Program, Oman Medical Specialty Board, Muscat, Oman
      sug:
        subj:
          Antiphospholipid Syndrome Complications
          Pyoderma Gangrenosum Etiology
          Pyoderma Gangrenosum Diagnosis
          Pyoderma Gangrenosum Drug Therapy
          Treatment Outcomes
          Female
          Middle Age
          Adrenal Cortex Hormones Administration and Dosage
          Cyclosporine Administration and Dosage
          Antibodies, Monoclonal Administration and Dosage
          Blood Transfusion
          Hematologic Tests
          Middle Aged: 45-64 years
          Female
      ab: We report a rare case of a middle-aged Omani woman who was known to have primary antiphospholipid syndrome, glucose-6-phosphate dehydrogenase deficiency, and iron deficiency anaemia. Cannulation attempts caused bulla which progressed to ulceration. A pathergy phenomenon with high suspicion of pyoderma gangrenosum was postulated. Management with corticosteroids, cyclosporin, and finally ustekinumab, a novel biologic agent, yielded a beneficial response.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        Journal Article
      ougenre: Article
    language: English
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