Comparison of Borrowing Methods for Incorporating Historical Data in Single-Arm Phase II Clinical Trials.

Background: Over the last few years, many efforts have been made to leverage historical information in clinical trials. Incorporating historical data into current trials allows for a more efficient design, smaller studies, or shorter duration and may potentially increase the relative amount of infor...

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Bibliographic Details
Published in:Therapeutic Innovation & Regulatory Science Vol. 59; no. 1; pp. 20 - 31
Main Authors: Urru, Sara, Verbeni, Michela, Azzolina, Danila, Baldi, Ileana, Berchialla, Paola
Format: equations & formulas research tables/charts Journal Article
Published: Springer Nature Jan2025
Online Access:View this record in EBSCOhost