Rapid and Sustained Resolution of Peristomal Pyoderma Gangrenosum With Aerosol Steroid Treatment.

BACKGROUND: Peristomal pyoderma gangrenosum (PPG) is a non-infectious neutrophilic dermatosis most commonly seen in the context of ostomies in inflammatory bowel disease. The lack of established treatment guidelines and high-quality evidence in the form of randomized controlled trials present a majo...

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Detalles Bibliográficos
Publicado en:Journal of Wound, Ostomy & Continence Nursing Vol. 52; no. 1; pp. 81 - 84
Autores principales: Mitsaki, Kyriaki Stefania, Gaglani, Bindi, Sethi, Mieran
Formato: case study pictorial Journal Article
Publicado: Lippincott Williams & Wilkins Jan/Feb2025
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:BACKGROUND: Peristomal pyoderma gangrenosum (PPG) is a non-infectious neutrophilic dermatosis most commonly seen in the context of ostomies in inflammatory bowel disease. The lack of established treatment guidelines and high-quality evidence in the form of randomized controlled trials present a major challenge in PPG management, owing to the rarity of the condition. Treatment can be further complicated by difficulties in maintaining the stoma pouch seal with conventional topical corticosteroids. CASE: We present a case of PPG treated with aerosol steroid inhaler, highlighting the need for innovative solutions in the management of the condition to maintain the stoma pouch seal. CONCLUSION: We achieved rapid and sustained resolution with the aerosol steroid, thus sparing the need for systemic agents, and we would like to advocate for its licensed use in PPG.