Rapid and Sustained Resolution of Peristomal Pyoderma Gangrenosum With Aerosol Steroid Treatment.

BACKGROUND: Peristomal pyoderma gangrenosum (PPG) is a non-infectious neutrophilic dermatosis most commonly seen in the context of ostomies in inflammatory bowel disease. The lack of established treatment guidelines and high-quality evidence in the form of randomized controlled trials present a majo...

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Publicado en:Journal of Wound, Ostomy & Continence Nursing Vol. 52; no. 1; pp. 81 - 84
Autores principales: Mitsaki, Kyriaki Stefania, Gaglani, Bindi, Sethi, Mieran
Formato: case study pictorial Journal Article
Publicado: Lippincott Williams & Wilkins Jan/Feb2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan/Feb2025
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      pub: Lippincott Williams & Wilkins
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        atl: Rapid and Sustained Resolution of Peristomal Pyoderma Gangrenosum With Aerosol Steroid Treatment.
      aug:
        au:
          Mitsaki, Kyriaki Stefania
          Gaglani, Bindi
          Sethi, Mieran
        affil: Kyriaki Stefania Mitsaki, MBBCh, BSc (Hons), MSc, MRCP, Department of Dermatology, Northwick Park Hospital, London North West University Hospital NHS Trust, London, UK.
      sug:
        subj:
          Pyoderma Gangrenosum Diagnosis
          Steroids Therapeutic Use
          Doxycycline Therapeutic Use
          Fluticasone Therapeutic Use
          Aerosols Therapeutic Use
          Peristomal Skin Care
          Adult
          Male
          Skin Ulcer Etiology
          Biopsy Methods
          Skin Tests
          Microscopy
          Fluticasone Administration and Dosage
          Nebulizers and Vaporizers
          Pruritus
          Adult: 19-44 years
          Male
      ab: BACKGROUND: Peristomal pyoderma gangrenosum (PPG) is a non-infectious neutrophilic dermatosis most commonly seen in the context of ostomies in inflammatory bowel disease. The lack of established treatment guidelines and high-quality evidence in the form of randomized controlled trials present a major challenge in PPG management, owing to the rarity of the condition. Treatment can be further complicated by difficulties in maintaining the stoma pouch seal with conventional topical corticosteroids. CASE: We present a case of PPG treated with aerosol steroid inhaler, highlighting the need for innovative solutions in the management of the condition to maintain the stoma pouch seal. CONCLUSION: We achieved rapid and sustained resolution with the aerosol steroid, thus sparing the need for systemic agents, and we would like to advocate for its licensed use in PPG.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        Journal Article
      ougenre: Article
    language: English
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