Effects of Frozen Red Dragon Fruit Consumption on Metabolic Markers in Healthy Subjects and Individuals at Risk of Type 2 Diabetes.
Background/Objectives: The interest in creating new products to decrease the risk of developing non-communicable chronic diseases such as type 2 diabetes (T2D) is increasing. These products include traditional food sources used as part of diverse cultures around the world, such as dragon fruit. The...
| Publicado en: | Nutrients Vol. 17; no. 3; pp. 441 - 457 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
MDPI
Feb2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=182985126&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 182985126 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20726643 B0TT jtl: Nutrients issn: 20726643 maglogo: N pubinfo: dt: Feb2025 vid: 17 iid: 3 pid: 97109 pub: MDPI artinfo: ui: 182985126 182985126 182985126 10.3390/nu17030441 182985126 ppf: 441 ppct: 16 formats: tig: atl: Effects of Frozen Red Dragon Fruit Consumption on Metabolic Markers in Healthy Subjects and Individuals at Risk of Type 2 Diabetes. aug: au: Flores-Verastegui, Mildred Inna Marcela Coe, Shelly Tammam, Jonathan Almahjoubi, Haythim Bridle, Robyn Bi, Sabina Thondre, Pariyarath Sangeetha affil: Oxford Brookes Centre for Nutrition and Health, School of Sport, Nutrition and Allied Health Professions, Oxford Brookes University, Oxford OX3 0BP, UK or (M.I.M.F.-V.) sug: subj: Diabetes Mellitus, Type 2 Risk Factors Diabetes Mellitus, Type 2 Metabolism Fruit Therapeutic Use Fruit Pharmacodynamics Biological Markers Risk Assessment Blood Pressure Blood Glucose Insulin Blood Lipids Blood Antioxidants C-Reactive Protein Blood Human Male Female Young Adult Adult Randomized Controlled Trials Random Assignment Systolic Pressure Diastolic Pressure Blood Specimen Collection Methods Time Factors ROC Curve Treatment Outcomes Adult: 19-44 years Male Female ab: Background/Objectives: The interest in creating new products to decrease the risk of developing non-communicable chronic diseases such as type 2 diabetes (T2D) is increasing. These products include traditional food sources used as part of diverse cultures around the world, such as dragon fruit. The aim of this study was to investigate the effects of a frozen red dragon fruit (FRDF) beverage on blood pressure, glycaemic response (GR) and insulinaemic response (IR), lipid profile (LP), total antioxidant status (TAS), and C-reactive protein (CRP) levels in healthy subjects and individuals at risk of T2D. Methods: A parallel design trial (UREC registration number 211527; ClinicalTrials.gov registration number NCT05199636/19 January 2022) lasting four weeks and involving three testing sessions was conducted; participants were randomly assigned to one of two treatments (following general health guidance or consuming FRDF beverage). Systolic and diastolic blood pressures were taken; venous blood samples were collected to determine the LP and CRP levels; and capillary blood samples were taken before and after consuming a standard glucose drink to evaluate GR and IR at 15 min intervals (first hour) and 30 min intervals (second hour). Results: Eighteen participants completed this study, nine healthy (28.44 ± 5.20 years) and nine at risk (31.78 ± 12.11 years). The daily consumption of an FRDF-based beverage for four weeks by individuals at risk of T2D resulted in a reduction in blood pressure and IR–incremental area under the curve. The LP showed a downward trend, and a significant difference between treatments (p = 0.009) was found for CRP levels. Conclusions: Beverages based on FRDF may have the potential to decrease the risk of T2D. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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