Design, fabrication, and characterization of a user-friendly microfluidic device for studying liver zonation-on-chip (ZoC)

Liver zonation is a fundamental characteristic of hepatocyte spatial heterogeneity, which is challenging to recapitulate in traditional cell cultures. This study presents a novel microfluidic device designed to induce zonation in liver cell cultures by establishing an oxygen gradient using standard...

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Bibliographic Details

Published in:	Biomedical Microdevices Vol. 27; no. 1; pp. 1 - 17
Main Authors:	Mahdavi, Reza, Hashemi-Najafabadi, Sameereh, Ghiass, Mohammad Adel, Valaskivi, Silmu, Välimäki, Hannu, Kreutzer, Joose, Hamngren Blomqvist, Charlotte, Romeo, Stefano, Kallio, Pasi, Adiels, Caroline Beck
Format:	Journal Article
Published:	Springer Nature Mar2025
Online Access:	View this record in EBSCOhost