Preserved learning despite impaired short-term memory in older adults with mild cognitive impairment.
Background: The impact of amnestic mild cognitive impairment (aMCI) on short-term memory (STM) and learning performance assessed with different memory modalities was unknown. This study examined differences in STM and learning ability between verbal and visuospatial memory-modalities in older adults...
| Publicado en: | Frontiers in Aging Neuroscience pp. 1 - 9 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Frontiers Media S.A.
2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=184195397&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 184195397 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 16634365 BG2U jtl: Frontiers in Aging Neuroscience issn: 16634365 maglogo: N pubinfo: dt: 2025 pid: 40038 pub: Frontiers Media S.A. artinfo: ui: 184195397 184195397 184195397 10.3389/fnagi.2025.1560791 184195397 ppf: 1 ppct: 8 formats: tig: atl: Preserved learning despite impaired short-term memory in older adults with mild cognitive impairment. aug: au: Smith, Elaina Cortez, Christopher Wiechmann, April Davis, Sandra Dyson, Hannah Kucharski, Krystyn Ross, Sarah Kline, Geoffrey Mallet, Robert T. Shi, Xiangrong affil: Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, United States sug: subj: Memory, Short Term Evaluation Mild Cognitive Impairment In Old Age Learning Methods Visual Perception Spatial Perception Verbal Behavior Human Funding Source Texas Male Female Middle Age Aged Questionnaires Neuropsychological Tests Scales Executive Function Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background: The impact of amnestic mild cognitive impairment (aMCI) on short-term memory (STM) and learning performance assessed with different memory modalities was unknown. This study examined differences in STM and learning ability between verbal and visuospatial memory-modalities in older adults with aMCI. Methods: Thirty-nine aMCI subjects (71.5 ± 6.0 yrs) and 33 non-MCI (control) subjects (71.1 ± 5.7 yrs) of similar age and educational attainment consented to participate in the study. Short-term memory was assessed using Digit-Span-Test (DST), California-Verbal-Learning-Test-2nd edition – short-form (CVLT-II), and Brief-Visuospatial-Memory-Test-Revised (BVMT-R); CVLT-II and BVMT-R assessed verbal-and visuospatial-learning, respectively. Results: DST-Backward (p = 0.016) and DST-Sequencing (p < 0.001) scores were significantly lower in the aMCI vs. control subjects (Student's t-test), but DST-Forward scores did not differ (p = 0.237). Immediate and delayed free-recall scores in both CVLT-II (p < 0.001) and BVMT-R (p < 0.001) were lower in the aMCI subjects. The immediate free-recall scores in both tests improved with repeated trials (two-factor ANOVA: p < 0.001 for trial factor) to similar extents in the aMCI and control groups with no significant interaction of the trial and group factors (p = 0.266 in CVLT-II and p = 0.239 in BVMT-R). Significance: Amnestic MCI subjects have diminished STM but intact learning ability. Differences in STM of older adults with vs. without aMCI are more readily distinguished by word-verbal memory and/or visuospatial memory testing than digit-verbal memory testing. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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