Limited Sampling Strategy for Predicting the Area under Plasma Concentration–Time Curve of Nadolol in Healthy Subjects.

Nadolol is a hydrophilic β‐adrenoceptor blocker with a relatively long half‐life and negligible metabolism. It is a substrate of P‐glycoprotein and organic anion transporting polypeptide 1A2, and may serve as an in vivo probe drug for the assessment of drug–drug and food–drug interactions mediated b...

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Publicado en:Journal of Clinical Pharmacology Vol. 65; no. 5; pp. 621 - 628
Autores principales: Misaka, Shingen, Maejima, Yuko, Shimomura, Kenju
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell May2025
Acceso en línea:Ver este registro en EBSCOhost