| Sumario: | Polycyclic Aromatic Hydrocarbons (PAHs) exposure has been linked to asthma, but their individual and combined effects in children remain unclear. Using data from the 2003–2012 National Health and Nutrition Examination Survey (NHANES), we investigated the associations between PAHs and asthma through logistic regression, Weighted Quantile Sum (WQS) regression, Quantile g Computation (qg computation), and Bayesian Kernel Machine Regression (BKMR). Subgroup analyses revealed a significant impact of PAHs on asthma, particularly in males. The WQS model showed a marginally significant combined effect of 9 PAHs on asthma (Odds Ratio = 1.37, 95% Confidence Interval: 1.06–1.75). BKMR also indicated a positive association between combined PAH exposure and asthma. 2-Hydroxyfluorene and 1-Hydroxypyrene were identified as the most significant contributors. These findings suggest that mixed PAH exposure is associated with asthma risk in children.
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