The individual and combined effects of polycyclic aromatic hydrocarbons on asthma among US children: evidence from the NHANES study.

Polycyclic Aromatic Hydrocarbons (PAHs) exposure has been linked to asthma, but their individual and combined effects in children remain unclear. Using data from the 2003–2012 National Health and Nutrition Examination Survey (NHANES), we investigated the associations between PAHs and asthma through...

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Publicado en:International Journal of Environmental Health Research Vol. 35; no. 6; pp. 1684 - 1696
Autores principales: Yang, Yang, Hu, Yufang, Cui, Jiaqi, Li, Xiaodan, Zhang, Xinxin, Sun, Qi, Zhang, Qi
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Jun2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2025
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      pub: Taylor & Francis Ltd
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        10.1080/09603123.2024.2431246
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        atl: The individual and combined effects of polycyclic aromatic hydrocarbons on asthma among US children: evidence from the NHANES study.
      aug:
        au:
          Yang, Yang
          Hu, Yufang
          Cui, Jiaqi
          Li, Xiaodan
          Zhang, Xinxin
          Sun, Qi
          Zhang, Qi
        affil: Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China
      sug:
        subj:
          Polycyclic Hydrocarbons, Aromatic Adverse Effects
          Environmental Exposure Adverse Effects
          Asthma Epidemiology
          Asthma Risk Factors
          Risk Assessment
          Sex Factors
          Human
          Male
          Female
          Child
          United States
          Cross Sectional Studies
          Questionnaires
          Logistic Regression
          Kruskal-Wallis Test
          Descriptive Statistics
          Data Analysis Software
          Urinalysis
          Creatinine Urine
          Air Pollution Adverse Effects
          Probability
          Odds Ratio
          Confidence Intervals
          Child: 6-12 years
          Male
          Female
      ab: Polycyclic Aromatic Hydrocarbons (PAHs) exposure has been linked to asthma, but their individual and combined effects in children remain unclear. Using data from the 2003–2012 National Health and Nutrition Examination Survey (NHANES), we investigated the associations between PAHs and asthma through logistic regression, Weighted Quantile Sum (WQS) regression, Quantile g Computation (qg computation), and Bayesian Kernel Machine Regression (BKMR). Subgroup analyses revealed a significant impact of PAHs on asthma, particularly in males. The WQS model showed a marginally significant combined effect of 9 PAHs on asthma (Odds Ratio = 1.37, 95% Confidence Interval: 1.06–1.75). BKMR also indicated a positive association between combined PAH exposure and asthma. 2-Hydroxyfluorene and 1-Hydroxypyrene were identified as the most significant contributors. These findings suggest that mixed PAH exposure is associated with asthma risk in children.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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