Enhancing antioxidant yield from carob (Ceratonia siliqua L.): evaluating the efficacy of maceration and ultrasound-assisted methods.

Our study aimed to optimize carob antioxidant extraction for use in the food, cosmetic, and pharmaceutical industries. Maceration investigated ethanol concentration, extraction temperature, and time, while ultrasound-assisted extraction examined ethanol concentration, ultrasound power, and time. A c...

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Publicado en:International Journal of Environmental Health Research Vol. 35; no. 7; pp. 1793 - 1806
Autores principales: Ben Hamouda, Ghofrane, Bettaieb Rebey, Iness, Zar Kalai, Feten, Hammami, Majdi, Ksouri, Riadh
Formato: equations & formulas research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Jul2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2025
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        atl: Enhancing antioxidant yield from carob (Ceratonia siliqua L.): evaluating the efficacy of maceration and ultrasound-assisted methods.
      aug:
        au:
          Ben Hamouda, Ghofrane
          Bettaieb Rebey, Iness
          Zar Kalai, Feten
          Hammami, Majdi
          Ksouri, Riadh
        affil: Laboratory of Medicinal and Aromatic Plants, Biotechnology Center of Borj-Cedria, Hammam-Lif, Tunisia
      sug:
        subj:
          Plant Extracts Therapeutic Use
          Plant Extracts Analysis
          Plants, Edible
          Antioxidants Pharmacodynamics
          Ultrasonography Methods
          Food
          Cosmetics
          Pharmaceutical Companies
          Human
          Models, Statistical
          Cluster Analysis
          Regression
          Multivariate Analysis
          Experimental Studies
          Comparative Studies
          Ethanol
          Descriptive Statistics
          Data Analysis Software
      ab: Our study aimed to optimize carob antioxidant extraction for use in the food, cosmetic, and pharmaceutical industries. Maceration investigated ethanol concentration, extraction temperature, and time, while ultrasound-assisted extraction examined ethanol concentration, ultrasound power, and time. A central composite design with 19 experimental points assessed the influence of variables on total yield, total phenolic content, and antioxidant activity. The results were analyzed to optimize the extraction parameters and enhance the antioxidant extraction from carob. The results of the study show that the best maceration condition for extracting antioxidants from the plant material was found to have a time of 24.38 minutes, an ethanol content of 59.02%, and a temperature of 54.52°C. Similarly, the optimal conditions for ultrasound-assisted extraction were found to be 51.49 minutes, 79.78% sonication power, and 76.12% alcohol. The optimal conditions identified can be used as a starting point for further optimization and scaling up of the extraction process.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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