Diagnosis of Drug-Resistant Tuberculosis: Rapid Evaluation of Drug Susceptibility with Nanopore Targeted Sequencing.
Background Whole-genome sequencing (WGS) has limitations in clinical diagnostics due to host DNA interference and lower pathogen load in clinical samples compared to cultured isolates, which reduce the effective sequencing depth and compromise the detection of resistance-associated mutations. As our...
| Publicado en: | Clinical Chemistry Vol. 71; no. 8; pp. 908 - 920 |
|---|---|
| Autores principales: | , , , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Oxford University Press / USA
Aug2025
|
| Acceso en línea: | Ver este registro en EBSCOhost |