Diagnosis of Drug-Resistant Tuberculosis: Rapid Evaluation of Drug Susceptibility with Nanopore Targeted Sequencing.

Background Whole-genome sequencing (WGS) has limitations in clinical diagnostics due to host DNA interference and lower pathogen load in clinical samples compared to cultured isolates, which reduce the effective sequencing depth and compromise the detection of resistance-associated mutations. As our...

Full description

Bibliographic Details

Published in:	Clinical Chemistry Vol. 71; no. 8; pp. 908 - 920
Main Authors:	Chen, Jun, Fan, Qijing, Gong, Shiwei, Guo, Jianjian, Rao, Youyi, Chen, Lifeng, Wang, Ying, Liao, Rui, Zhang, Zhengbin, Liu, Chang, Wu, Ming, Chen, Shi, Ren, Yi
Format:	Journal Article
Published:	Oxford University Press / USA Aug2025
Online Access:	View this record in EBSCOhost