Ventilator-Associated Pneumonia in Patients Using Proton Pump Inhibitors Versus Histamine H2 Receptor Antagonists: A Systematic Review and Meta-Analysis.

Background: The common use of proton pump inhibitors (PPIs) and histamine 2 receptor antagonists (H2RA) in critically ill patients may increase the incidence of pneumonia associated with mechanical ventilation caused by alkalinization of gastric pH and microaspirations. Given the differences in the...

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Bibliographic Details
Published in:Respiratory Care Vol. 70; no. 9; pp. 1159 - 1168
Main Authors: Alves Filho, Francisco Willamy Pedrosa, Lima, Nágila Alves, Mendes, Beatriz Ximenes, Sales, Ivna Cavalcante Barros
Format: meta analysis research systematic review tables/charts Journal Article
Published: Mary Ann Liebert, Inc. Sep2025
Online Access:View this record in EBSCOhost