Improvement in Mitral Regurgitation After Catheter Ablation of Premature Ventricular Complexes.
Background: Frequent premature ventricular complexes (PVC) can lead to left ventricular (LV) dysfunction. Reduction of PVC burden can result in improvement of LV function. Whether successful PVC ablation can also result in improvement of mitral regurgitation (MR) in patients with frequent PVCs and M...
| Publicado en: | Journal of Cardiovascular Electrophysiology Vol. 36; no. 9; pp. 2188 - 2196 |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Sep2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187860104&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187860104 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10453873 GSB jtl: Journal of Cardiovascular Electrophysiology issn: 10453873 maglogo: Y pubinfo: dt: Sep2025 vid: 36 iid: 9 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 187860104 186448915 187860104 187860104 10.1111/jce.16781 187860104 ppf: 2188 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Improvement in Mitral Regurgitation After Catheter Ablation of Premature Ventricular Complexes. aug: au: Tokavanich, Nithi Alaka, Abiola Tye, Michael Chakrabarti, Apurba Goraya, Sayhaan Yoder, Mason Madamanchi, Chaitanya Arps, Kelly Shah, Muazzum Deshmukh, Amrish Ghannam, Michael Cunnane, Ryan Jongnarangsin, Krit Crawford, Thomas Chugh, Aman Latchamsetty, Rakesh Oral, Hakan Morady, Fred Bogun, Frank Liang, Jackson J. affil: Section of Cardiac Electrophysiology, University of Michigan Medical Center, Cardiovascular Center, Ann Arbor Michigan,, USA sug: subj: Mitral Valve Insufficiency Therapy Premature Ventricular Contractions Therapy Catheter Ablation Human Retrospective Design Record Review Descriptive Statistics Male Female Middle Age Aged T-Tests Analysis of Variance Chi Square Test Fisher's Exact Test Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background: Frequent premature ventricular complexes (PVC) can lead to left ventricular (LV) dysfunction. Reduction of PVC burden can result in improvement of LV function. Whether successful PVC ablation can also result in improvement of mitral regurgitation (MR) in patients with frequent PVCs and MR remains unclear. Objective: We aimed to evaluate the impact of PVC ablation on the degree of MR in patients with patients with frequent PVCs and MR. Method: We retrospectively analyzed patients with MR and frequent PVCs who underwent PVC ablation from January 2015 to December 2024. Severity of MR was compared between pre‐ and post‐PVC ablation to identify improvement of valvular regurgitation. Results: A total of 47 patients were included in the study. All patients had at least mild MR (6 with mild MR, 17 mild‐moderate MR, 19 moderate MR, 3 moderate‐severe MR, and 2 severe MR). The mean PVC burdens before versus after ablation were 23.5 ± 11% and 4 ± 4.1% (p = 0.02), respectively. Improvement (by ≥ 1 grade) of MR was seen in 30 of 47 (64%) patients after ablation. Among patients with > 80% PVC reduction after ablation, 19 of 29 (65.5%), 50%–80% PVC reduction, 9 of 13 (69%), and < 50% PVC reduction, 2 of 5 (40%) showed improvement of MR. All 5 of (100%) patients with greater than moderate MR demonstrated an improvement in MR severity after PVC ablation. Conclusion: There appears to be a trend toward an MR improvement with reduction in PVC burden after successful PVC ablation. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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