Glycemic responses of three mango varieties in subjects with and without T2D: a pilot crossover study using OTT and CGM.

Objectives: Mango consumption is often restricted in diet consumed by people with diabetes due to concerns about its glycemic impact. This study aimed to compare the glycemic effects of mango consumption with those of white bread and glucose in subjects with and without type 2 diabetes (T2D). Method...

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Publicado en:European Journal of Clinical Nutrition Vol. 79; no. 10; pp. 991 - 1000
Autores principales: Kehar, Sugandha, Bhatt, Surya Prakash, Pandey, Ravindra M., Ahmad Ansari, Irshad, Palavalli, Rajashekar Reddy, Gupta, Vimal, Misra, Anoop
Formato: research tables/charts Journal Article
Publicado: Springer Nature Oct2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2025
      vid: 79
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      pub: Springer Nature
      place: New York, New York
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        10.1038/s41430-025-01659-1
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        atl: Glycemic responses of three mango varieties in subjects with and without T2D: a pilot crossover study using OTT and CGM.
      aug:
        au:
          Kehar, Sugandha
          Bhatt, Surya Prakash
          Pandey, Ravindra M.
          Ahmad Ansari, Irshad
          Palavalli, Rajashekar Reddy
          Gupta, Vimal
          Misra, Anoop
        affil: https://ror.org/03ejqwd09 Diabetes Foundation (India), New Delhi, India
      sug:
        subj:
          Fruit
          Bread
          Dietary Carbohydrates
          Food Intake
          Glycemic Control
          Blood Glucose
          Diabetes Mellitus, Type 2 Metabolism
          Glucose Tolerance Test
          Continuous Glucose Monitoring
          Funding Source
          India
          Human
          Pilot Studies
          Crossover Design
          Postprandial Period
          ROC Curve
          Descriptive Statistics
          Glycemic Index
          Glycemic Load
          Adult
          Middle Age
          Male
          Female
          Comparative Studies
          Insulin Blood
          Chemiluminescent Measurements
          Immunoassay
          Randomized Controlled Trials
          Random Assignment
          Macronutrients
          Chi Square Test
          One-Way Analysis of Variance
          Kruskal-Wallis Test
          Multiple Linear Regression
          Repeated Measures
          Data Analysis Software
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Objectives: Mango consumption is often restricted in diet consumed by people with diabetes due to concerns about its glycemic impact. This study aimed to compare the glycemic effects of mango consumption with those of white bread and glucose in subjects with and without type 2 diabetes (T2D). Methods: We conducted a two-phase study involving 95 participants (45 with T2D, 50 non-diabetic). Phase 1 employed oral tolerance test (OTT) to assess immediate glycemic responses to mango (Safeda, Dasheri, and Langra), bread, and glucose. Phase 2 utilized continuous glucose monitoring (CGM) to evaluate glycemic profiles over three days. Results: On OTT, in non-diabetic subjects, mango consumption resulted in non-significantly lower postprandial glucose peaks compared to glucose and bread, except Langra variety which showed lowest area under the curve for glucose of borderline significance. In subjects with T2D, mango varieties performed similarly to bread. CGM data revealed that mango consumption over three days resulted in a similar glycemic profile to bread in non-diabetic subjects and a lower glycemic profile in subjects with T2D, though most differences were statistically not significant. Mean Amplitude of Glycemic Excursion (MAGE) was significantly lower after mango ingestion as compared to bread in CGM data in subjects with T2D. Conclusions: Data show limited glycemic impact of tested mango varieties, comparable to or lower than white bread, especially in T2D subjects. The significant reduction in MAGE observed with mango consumption suggests potential benefits for glycemic variability. With portion control in calorie restrictive diets, mango may be suitable for people with T2D.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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