Comparison of HMGB1, RAGE, TLR4, and NF-κB levels in children and adolescents diagnosed with autism spectrum disorder with healthy controls.

Introduction: The objective of our study is to clarify the involvement of the HMGB1/RAGE/TLR4/NF-kB axis, a crucial component in inflammation, in the etiopathogenesis of autism spectrum disorder (ASD). Method: We analyzed the levels of HMGB1, RAGE, TLR4, and NF-kB in serum from 80 children (40 with...

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Publicado en:International Journal of Developmental Disabilities Vol. 71; no. 7; pp. 1073 - 1081
Autores principales: Kıyat, Esra, Aktepe, Evrim, Kumbul Doğuç, Duygu, Bedir, Mehmet, Ertürk, Emre, Işık, Ümit
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Nov2025
Acceso en línea:Ver este registro en EBSCOhost