Developmental differences in threat learning are associated with changes in frontal-central theta activity.
Major theories link variations in threat learning to the emergence of anxiety symptoms, especially during adolescence. Despite significant neural maturation of threat learning circuitry during this developmental stage, research on adolescence-specific neural responses during threat learning is limit...
| Publicado en: | European Child & Adolescent Psychiatry Vol. 34; no. 11; pp. 3387 - 3400 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Nov2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=189593485&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 189593485 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10188827 EJ3 jtl: European Child & Adolescent Psychiatry issn: 10188827 maglogo: N pubinfo: dt: Nov2025 vid: 34 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 189593485 185442113 189593485 189593485 10.1007/s00787-025-02745-2 189593485 ppf: 3387 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Developmental differences in threat learning are associated with changes in frontal-central theta activity. aug: au: Shner-Livne, Gil Barak, Nadav Shitrit, Ido Abend, Rany Shechner, Tomer affil: https://ror.org/02f009v59 School of Psychological Sciences and the Integrated Brain and Behavior Research Center, University of Haifa, Abba Hushi 199, Mt Carmel, Haifa, Israel sug: subj: Conditioning (Psychology) Evaluation Reinforcement (Psychology) Evaluation Fear Evaluation Frontal Lobe Physiology Learning Evaluation Electroencephalography Evaluation Human Male Female Child Adolescence Adult Anxiety Psychosocial Factors Behavior Evaluation Emotions Neural Pathways Physiology Temporal Lobe Physiology Evoked Potentials, Auditory, Brainstem Physiology Cues Safety Biological Markers Analysis Sleep Duration Sleep Quality Questionnaires Anxiety Psychosocial Factors Repeated Measures Analysis of Covariance Post Hoc Analysis Sensory Stimulation Neural Transmission Physiology Descriptive Statistics Data Analysis Software Child: 6-12 years Adolescent: 13-18 years Adult: 19-44 years Male Female ab: Major theories link variations in threat learning to the emergence of anxiety symptoms, especially during adolescence. Despite significant neural maturation of threat learning circuitry during this developmental stage, research on adolescence-specific neural responses during threat learning is limited. This study was the first to examine threat learning mechanisms through neural frequency activity among youth, focusing on activity in the theta (4–7 Hz) and alpha (8–12 Hz) frequency bands. Sixty-three adolescents and 65 adults completed a two-day threat acquisition and extinction procedure, while brain activity was measured using electroencephalography (EEG). Analyses focused on developmental differences in high temporal resolution changes in frequency activity, distinguishing between induced and evoked EEG signals. Developmental differences were mainly observed in frontal-central theta activity. During acquisition, adolescents showed higher induced theta activity to both threat and safety cues than adults. During extinction, adults showed decreased evoked theta activity to the conditioned stimulus, indicating effective inhibition of threat representations; in contrast, adolescents exhibited persistent threat contingencies throughout extinction. Both groups showed consistent alpha suppression towards the threat cue, suggesting sustained vigilance even during late extinction. Frontal-central theta activity is a valuable marker for capturing differences between adolescents and adults in threat learning. These findings add to mechanistic research efforts aiming to uncover factors contributing to anxiety vulnerability during adolescence. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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