Tolerability, Safety, and Pharmacokinetics of Ivermectin After Nasal Application in Healthy Adult Subjects.

Nasal epithelium is the site of infection for SARS‐CoV2 viruses, with interactions of the viral spike protein with the ACE2 receptor of the host cell. Molecular docking studies have shown that ivermectin shields the spike protein and thereby prevents binding to ACE2. Nasal application of high doses...

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Bibliographic Details
Published in:Journal of Clinical Pharmacology Vol. 66; no. 1; pp. 1 - 18
Main Authors: Wissel, Stefan, Wissel, Philipp, Rischer, Matthias, Häberlein, Felix, Riethmüller‐Winzen, Hilde, Häberlein, Hanns
Format: research tables/charts randomized controlled trial Journal Article
Published: Wiley-Blackwell Jan2026
Online Access:View this record in EBSCOhost