Tolerability, Safety, and Pharmacokinetics of Ivermectin After Nasal Application in Healthy Adult Subjects.

Nasal epithelium is the site of infection for SARS‐CoV2 viruses, with interactions of the viral spike protein with the ACE2 receptor of the host cell. Molecular docking studies have shown that ivermectin shields the spike protein and thereby prevents binding to ACE2. Nasal application of high doses...

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Publicado en:Journal of Clinical Pharmacology Vol. 66; no. 1; pp. 1 - 18
Autores principales: Wissel, Stefan, Wissel, Philipp, Rischer, Matthias, Häberlein, Felix, Riethmüller‐Winzen, Hilde, Häberlein, Hanns
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Wiley-Blackwell Jan2026
Acceso en línea:Ver este registro en EBSCOhost