The ORB2 RNA-binding protein negatively regulates its target transcripts during the Drosophila maternal-to-zygotic transition via its functionally conserved Zinc-binding "ZZ" domain.

Posttranscriptional regulation is particularly prominent during the maternal-to-zygotic transition (MZT), a developmental phase during which a large proportion of maternally provided mRNAs is repressed and cleared from metazoan embryos. RNA-binding proteins (RBPs) are key components of the posttrans...

Descripción completa

Detalles Bibliográficos
Publicado en:Genetics Vol. 232; no. 2; pp. 1 - 23
Autores principales: Low, Timothy C H, Luo, Hua, Weerasooriya, Chalini, Wang, Zhuyi, Lin, Sichun, Karaiskakis, Angelo, Angers, Stephane, Smibert, Craig A, Lipshitz, Howard D
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA Feb2026
Acceso en línea:Ver este registro en EBSCOhost