Depleting retinoic acid synthesis in the nucleus accumbens shell produces a protective phenotype for emotional reactivity and drug-taking in rats.

Rationale: In previous work, a convergent transcriptomic approach strongly suggested a role for retinoic acid (RA) in controlling the emotion- and reward-related functions of the nucleus accumbens shell (NAcSh). Objective: Here, we causally assess the role of NAcSh RA in controlling anxiety-, emotio...

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Bibliographic Details
Published in:Psychopharmacology Vol. 243; no. 1; pp. 59 - 75
Main Authors: Mármol Contreras, Yorkiris, Dvorak, Nolan M., Tapia, Cynthia M., Zaman, Roxana, Annareddy, Jyothika, Balikosa, Yves, Gupta, Nikita S., Rader, Alex P., Vasquez, Tileena E. S., Koshy, Shyny, Li, Dingge, Balaji, Varun K., Laezza, Fernanda, Green, Thomas A.
Format: Journal Article
Published: Springer Nature Jan2026
Online Access:View this record in EBSCOhost