Risk Factors of Frailty in People with Hematologic Malignancies: A Systematic Review and Meta-Analysis.
Due to the burden of diseases and adverse reactions to treatment, people with hematologic malignancies usually experience frailty. This study determined the risk factors associated with frailty in people with hematologic malignancies. A thorough examination of the literature was conducted across nin...
| Publicado en: | Pacific Rim International Journal of Nursing Research Vol. 30; no. 1; pp. 269 - 287 |
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| Autores principales: | , , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Thailand Nursing & Midwifery Council
Jan-Mar2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=191555825&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 191555825 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19068107 B7IM jtl: Pacific Rim International Journal of Nursing Research issn: 19068107 maglogo: N pubinfo: dt: Jan-Mar2026 vid: 30 iid: 1 pid: 26313 pub: Thailand Nursing & Midwifery Council artinfo: ui: 191555825 191555825 191555825 10.60099/prijnr.2026.275617 191555825 ppf: 269 ppct: 18 formats: fmt: @attributes: type: P tig: atl: Risk Factors of Frailty in People with Hematologic Malignancies: A Systematic Review and Meta-Analysis. aug: au: Zhang, Ying Du, Ruofei Du, Yating Li, Jin Lu, Yanli Zhao, Xiaoqiang Wang, Yingfang Yang, Huimin affil: RN, PhD, School of Nursing, Henan University of Science and Technology, Luoyang, China sug: subj: Hematologic Neoplasms Complications Frailty Syndrome Risk Factors Risk Assessment Human Systematic Review Meta Analysis Descriptive Statistics Data Analysis Software PubMed Embase CINAHL Database Scales Frailty Syndrome Epidemiology Grip Strength Physical Activity Comorbidity Neoplasm Staging Biological Markers Multidisciplinary Care Team Confidence Intervals Odds Ratio Funding Source ab: Due to the burden of diseases and adverse reactions to treatment, people with hematologic malignancies usually experience frailty. This study determined the risk factors associated with frailty in people with hematologic malignancies. A thorough examination of the literature was conducted across nine databases following the PRISMA guidelines, including PubMed, Web of Science Core Collection, Embase, CINAHL, CNKI, Wanfang Data, CBM, VIP Database, and SinoMed, covering the period from 2001 to July 26, 2024. The Newcastle-Ottawa Scale was used to assess the quality of the included studies, in conjunction with evaluation tools from the Agency for Healthcare Research and Quality. The analysis included 23 studies, encompassing 13,849 participants. A high prevalence of frailty was observed in this study, affecting 27.1% of the participants involved. Several risk factors for frailty were identified, including demographic traits (gender, age), clinical features (hand grip strength, physical activity, comorbidities, advanced disease stages, neurological symptoms), biochemical markers (albumin levels, interleukin-6), and mental state (anaemia, depressive symptoms). Our analysis suggests that frailty is common among people with hematologic malignancies. Nurses should pay attention to individuals who exhibit the above-mentioned influencing factors in clinical practice, prevent the occurrence and progression of frailty, and engage in multidisciplinary collaboration and multi-targeted interventions to better manage individuals with frailty. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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